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Transition-Metal-Free Multicomponent Benzannulation Reactions for the Construction of Polysubstituted Benzene Derivatives

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journal contribution
posted on 06.11.2015, 00:00 authored by Wen-Ming Shu, Kai-Lu Zheng, Jun-Rui Ma, An-Xin Wu
A transition-metal-free multicomponent benzannulation reaction was developed from readily available ketones, nitro-olefins, and diester acetylenedicarboxylate. This approach provides a straightforward and efficient way to construct polysubstituted benzene derivatives under mild conditions in high yields.