American Chemical Society
jo7b00767_si_001.pdf (3.61 MB)

Transition-Metal-Free and Oxidant-Free Cross-Coupling of Arylhydrazines with Disulfides: Base-Promoted Synthesis of Unsymmetrical Aryl Sulfides

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journal contribution
posted on 2017-06-15, 00:00 authored by Toshihide Taniguchi, Takuya Naka, Mitsutaka Imoto, Motonori Takeda, Takeo Nakai, Masatoshi Mihara, Takumi Mizuno, Akihiro Nomoto, Akiya Ogawa
A novel synthesis of unsymmetrical aryl sulfides, which requires no transition metal catalyst and no oxidant, was developed. This base-promoted cross-coupling reaction proceeded using arylhydrazines and 1 equiv amount of disulfides under inert gas conditions to afford the unsymmetrical aryl sulfides in good yields.