Transfer Hydrogenation
of Ketones and Imines with
Methanol under Base-Free Conditions Catalyzed by an Anionic Metal–Ligand
Bifunctional Iridium Catalyst
posted on 2020-01-22, 18:37authored byRongzhou Wang, Xingyou Han, Jing Xu, Peng Liu, Feng Li
An anionic iridium
complex [Cp*Ir(2,2′-bpyO)(OH)][Na] was
found to be a general and highly efficient catalyst for transfer hydrogenation
of ketones and imines with methanol under base-free conditions. Readily
reducible or labile substituents, such as nitro, cyano, and ester
groups, were tolerated under present reaction conditions. Notably,
this study exhibits the unique potential of anionic metal–ligand
bifunctional iridium catalysts for transfer hydrogenation with methanol
as a hydrogen source.