Transalkylation via C–N Bond Cleavage of Amines Catalyzed by Super Organophotoreductant CBZ6

The super organoreductant CBZ6-catalyzed tandem transalkylation–cyclization using amines as traceless radical donors and stabilizer is reported. The later-stage breaking of an N–C bond enables the transalkylation with a secondary amine as the leaving moiety. A wide range of tertiary amines were used as alkyl radical donors for the C1–C8 alkyls. This traceless stabilizer also enabled the transalkylation with methyl radical, which is normally not possible because of the instability of methyl radical.