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Total Synthesis of the Potent Antitumor Polyketide (−)-Callystatin A

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journal contribution
posted on 10.06.2005, 00:00 by Luiz C. Dias, Paulo R. R. Meira
A highly convergent and efficient total synthesis of the potent antitumor polyketide (−)-callystatin A is described. The synthesis required 19 steps from N-propionyl oxazolidinone 23 and produced the desired product in 3.5% overall yield.