ol502459p_si_001.pdf (12.89 MB)

Total Synthesis of Russuphelol: A Case of Mistaken Chirality

Download (12.89 MB)
journal contribution
posted on 19.09.2014, 00:00 by M. Quamar Salih, Christopher M. Beaudry
The chlorohydroquinone tetramer, russuphelol, does not have stereocenters; however, it was reported as a chiral optically active substance with stable enantiomeric conformations. The natural product is synthesized in six steps and 14% overall yield. Synthetic material was used to experimentally investigate its chiral properties.