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Total Synthesis of Debromoflustramine B via Biomimetic Alkylative Cyclization

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journal contribution
posted on 22.04.2003, 00:00 by Gan Hup Tan, Xiuwen Zhu, A. Ganesan
The hexahydropyrrolo[2,3-b]indoline skeleton is readily accessed by the zinc triflate-mediated alkylation of tryptamine derivatives. The methodology was employed in a three-step total synthesis of debromoflustramine B.