American Chemical Society
ol702907u_si_002.pdf (3.37 MB)

Total Synthesis of (±)-Crinine via the Regioselective Stille Coupling and Diels−Alder Reaction of 3,5-Dibromo-2-pyrone

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journal contribution
posted on 2008-02-21, 00:00 authored by Nguyen Thanh Tam, Cheon-Gyu Cho
The regioselective synthesis and Diels−Alder cycloaddition of 3-(3,4-methylenedioxyphenyl)-5-bromo-2-pyrone provided a new synthetic route to crinine. The vinyl bromide group can be used as a handle for further derivatization.