ol0168263_si_001.pdf (22.81 kB)
Download file

Total Synthesis of Crambescidin 359

Download (22.81 kB)
journal contribution
posted on 29.12.2001, 00:00 by Kazuo Nagasawa, Angelina Georgieva, Hiroyuki Koshino, Tadashi Nakata, Tetsuya Kita, Yuichi Hashimoto
Crambescidin 359 (4), which is the “vessel part” of the pentacyclic guanidine alkaloid ptilomycalin A (1), was synthesized for the first time based upon successive 1,3-dipolar cycloaddition reaction. This synthesis established the absolute stereochemistry of 4.

History