ol902525k_si_001.pdf (1.58 MB)
Download file

Total Synthesis and Absolute Configuration of (−)-Berkeleyamide A

Download (1.58 MB)
journal contribution
posted on 05.02.2010, 00:00 by Jonathan Sperry, Eric B. J. Harris, Margaret A. Brimble
A chiral-pool approach to (−)-berkeleyamide A 1 based on a diastereoselective nitrile oxide [3 + 2]-cycloaddition completes the first total synthesis establishing the absolute stereochemistry of the natural product.

History