ja070336+_si_004.pdf (1.66 MB)
Download file

Total Syntheses of (+)-Lyconadin A and (−)-Lyconadin B

Download (1.66 MB)
journal contribution
posted on 02.04.2020, 14:16 by Douglas C. Beshore, Amos B. Smith
The enantioselective syntheses of (+)-lyconadin A and (−)-lyconadin B are described. Key bond constructions include a strategy-level intramolecular aldol/conjugate addition cascade, an olefin aminoiodination, and a novel one-pot α-pyridinone annulation.

History