Tigliane Diterpenoids from the Stem Bark of Neoboutonia macrocalyx

Neoboutonia macrocalyx is a plant used by traditional healers among the Meru community in Kenya. Chromatographic fractionation of the petroleum ether and dichloromethane extracts of this plant yielded one known (1) and three new tigliane-type diterpenoids (2−4). The chemical structures of the isolated compounds were established through spectroscopic data interpretation.