American Chemical Society
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The First Synthesis of a Thioglycoside Analogue of the Immunostimulant KRN7000

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journal contribution
posted on 2008-10-16, 00:00 authored by Ravindra T. Dere, Xiangming Zhu
The first total synthesis of a thioglycoside analogue of KRN7000, a potential immunostimulant, is described. Two key intermediates are α-galactosyl thiol 4 and phytosphingosine derivative 5, which were both prepared from d-galactose.