posted on 2008-10-16, 00:00authored byRavindra T. Dere, Xiangming Zhu
The first total synthesis of a thioglycoside analogue of KRN7000, a potential immunostimulant, is described. Two key intermediates are α-galactosyl thiol 4 and phytosphingosine derivative 5, which were both prepared from d-galactose.