ol020037j_si_001.pdf (952.25 kB)
Download fileThe First Stereoselective Ficini−Claisen Rearrangement Using Chiral Ynamides
journal contribution
posted on 2002-03-22, 00:00 authored by Jason A. Mulder, Richard P. Hsung, Michael O. Frederick, Michael R. Tracey, Craig A. ZificsakThe first asymmetric Ficini−Claisen rearrangement using chiral ynamides is described. At relatively low temperatures, the Ficini−Claisen
rearrangement can be efficiently promoted by p-nitrobenzenesulfonic acid leading to high diastereoselectivity for a range of different allylic
alcohols and chiral ynamides.