American Chemical Society
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Synthetic Studies on Maitotoxin. 1. Stereoselective Synthesis of the C′D′E′F′-Ring System Having a Side Chain

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journal contribution
posted on 2008-05-01, 00:00 authored by Masayuki Morita, Seishi Ishiyama, Hiroyuki Koshino, Tadashi Nakata
The stereoselective synthesis of the maitotoxin C′D′E′F′-ring system having a side chain has been accomplished through a convergent strategy. The key reactions include Horner-Wadsworth-Emmons coupling of the C′D′E′-ring and the side chain and subsequent construction of the F′-ring by silane reduction of dihydropyran.