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Synthesis of the Indolizino[7,6-c]quinoline Alkaloid Isaindigotidione

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journal contribution
posted on 15.10.2010, 00:00 authored by Malik Hellal, Gregory D. Cuny
The first synthesis of isaindigotidione has been developed utilizing a reaction sequence including an asymmetric rhodium-catalyzed 1,4-conjugate addition, an intramolecular aldol reaction, and a lactamization.