Synthesis of the Indolizino[7,6-c]quinoline Alkaloid Isaindigotidione

Hellal, Malik; Cuny, Gregory D.

doi:10.1021/ol101890t.s001

Synthesis of the Indolizino[7,6-<i>c</i>]quinoline Alkaloid Isaindigotidione

https://doi.org/10.1021/ol101890t.s001
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posted on 2010-10-15, 00:00 authored by Malik Hellal, Gregory D. Cuny

The first synthesis of isaindigotidione has been developed utilizing a reaction sequence including an asymmetric rhodium-catalyzed 1,4-conjugate addition, an intramolecular aldol reaction, and a lactamization.

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DOI - Is supplement to Synthesis of the Indolizino[7,6-c]quinoline Alkaloid Isaindigotidione

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Keywords

lactamization Alkaloid isaindigotidione conjugate reaction sequence intramolecular aldol reaction Indolizino synthesis Isaindigotidione Synthesi

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