posted on 2019-07-25, 17:44authored bySubas
Chandra Sahoo, Subhas Chandra Pan
An unusual aerobic
hydrolysis-cascade reaction has been developed
with N-phenacylbenzothiazolium bromides by
treatment with organic and inorganic base. The corresponding N-formyl-2-benzoyl benzothiazoline and 2-substituted benzothiazole
products were obtained in moderate to good yields under mild reaction
conditions. Also, symmetrical disulfide was formed when keto group
was replaced with ester. The scopes of the reactions are fairly broad
tolerating aryl, heteroaryl, and alkyl groups.