posted on 2021-08-02, 16:37authored byYa Dong, Ruining Li, Junliang Zhou, Zhankui Sun
Herein we report a photocatalytic
oxidative radical addition reaction
for the synthesis of unsymmetrical 1,4-dicarbonyl compounds. This
reaction utilizes a desulfurization process to generate electrophilic
radicals, which add to α-halogenated alkenes and undergo further
oxidation to deliver 1,4-dicarbonyl compounds. This mild and highly
efficient method provides a valuable alternative to known strategies.