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Synthesis of Modified Oligodeoxyribonucleotides on a Solid-Phase Support via Derivatization of a Selectively Revealed 2‘-Amino-2‘-deoxyuridine

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journal contribution
posted on 17.11.1999, 00:00 by Jae-Taeg Hwang, Marc M. Greenberg
High yields of oligodeoxyribonucleotides modified at the C2‘-position of site specifically incorporated 2‘-amino-2‘-deoxyuridine are obtained by photolytically unmasking the nucleophile in an otherwise protected solid-phase support-bound biopolymer.