jo1018393_si_007.pdf (4.33 MB)

Synthesis of Isoxazoline N-Oxides via [Hydroxy(tosyloxy)iodo]benzene (HTIB)-Mediated Oxidative N−O Coupling

Download (4.33 MB)
journal contribution
posted on 21.01.2011, 00:00 by Mustafa J. Raihan, Veerababurao Kavala, Pateliya Mujjamil Habib, Qiao-Zhi Guan, Chun-Wei Kuo, Ching-Fa Yao
An HTIB mediated oxidative N−O coupling strategy for the synthesis of some isoxazoline N-oxide derivatives from β-hydroxyketoximes is described, along with a comparative study of the efficiency of N−O coupling in two different solvents. A plausible mechanism for the conversion is proposed.

History