American Chemical Society
ol101698a_si_001.pdf (1.03 MB)

Synthesis of Highly Fluorinated 2,2′-Biphenols and 2,2′-Bisanisoles

Download (1.03 MB)
journal contribution
posted on 2010-10-01, 00:00 authored by Robert Francke, Gregor Schnakenburg, Siegfried R. Waldvogel
Multiply fluorine-substituted iodo anisoles are efficiently coupled in an Ullmann-type reaction to provide the corresponding bisanisoles. The coupling is selective and even tolerates bromo moieties. Subsequent deprotection of hydroxy groups gives access to highly fluorinated biphenols.