posted on 2006-09-29, 00:00authored byRoberto J. Brea, M. Pilar López-Deber, Luis Castedo, Juan R. Granja
Mild conditions are described that allow the palladium-catalyzed cross-coupling of Cα-alkynylated glycine with a
wide variety of electron-rich and electron-poor aryl and
heteroaryl halides in aqueous media.