Synthesis of Diaryl Acetates and
Oxindoles via a Sequential VNSAr−SNAr
Three-Component Coupling Reaction

Lawrence, Nicholas J.; Davies, Christopher A.; Gray, Matthew

doi:10.1021/ol047890y.s001

ol047890y_si_001.pdf (99.42 kB)

Synthesis of Diaryl Acetates and Oxindoles via a Sequential VNS_Ar−S_NAr Three-Component Coupling Reaction

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posted on 2004-12-23, 00:00 authored by Nicholas J. Lawrence, Christopher A. Davies, Matthew Gray

The VNS and S_NAr reactions combine to form an efficient three-component one-pot route to diarylmethanes. The products of selected diaryl acetates provide modular 3-aryloxindole derivatives.

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S N Ar reactions VNS diaryl acetates Diaryl Acetates

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Synthesis of Diaryl Acetates and Oxindoles via a Sequential VNSAr−SNAr Three-Component Coupling Reaction