Synthesis of C–N or C–C Spiroindolines via Rearrangement Coupling Reaction

Herein, we report a general approach to effectively construct C–N or C–C spiroindolines using tetrahydro-β-carbolines as starting materials via a rearrangement coupling reaction. This method is characterized by its operational simplicity and mild conditions. Notably, a wide range of anilines and indoles are suitable for this intermolecular coupling, yielding the corresponding C–N or C–C spiroindolines in good to excellent yields.