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Synthesis of 2‑Aminophenols and Heterocycles by Ru-Catalyzed C–H Mono- and Dihydroxylation

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journal contribution
posted on 17.05.2013, 00:00 by Xinglin Yang, Gang Shan, Yu Rao
A novel and efficient synthesis of 2-aminophenols, 2-aminobenzene-1,3-diols, and heterocycles through Ru-catalyzed C–H mono- and dihydroxylation of anilides has been developed with a new directing group strategy. The reaction demonstrates excellent reactivity, regioselectivity, good functional group tolerance, and high yields.

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