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Synthesis and Use of a Trifluoromethylated Azomethine Ylide Precursor

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journal contribution
posted on 21.12.2012, 00:00 by Gaël Tran, Robin Meier, Lawrence Harris, Duncan L. Browne, Steven V. Ley
The presence of fluorous substituents can impart a dramatic effect on the efficacy of molecules used for a range of applications in society. Here, we describe the preparation and use of a new trifluoromethylated azomethine ylide precursor, which leads to a series of fluorinated pyrrolidine, 3-pyrroline, and pyrrole building blocks.