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Synthesis and Structural Revision of Symbiodinolide C23−C34 Fragment

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journal contribution
posted on 03.07.2009, 00:00 by Takeshi Murata, Masayuki Sano, Hiroyoshi Takamura, Isao Kadota, Daisuke Uemura
Stereoselective synthesis of the C23−C34 fragment of symbiodinolide, which possesses the originally proposed stereochemistry, and its diastereomers was achieved in 19 steps from l-aspartic acid, respectively. Comparison of spectroscopic data of the synthetic products with those of the degraded product of symbiodinolide led to a structural revision of the C23−C34 fragment.