posted on 2014-01-06, 00:00authored bySarah R. Spell, Nicholas P. Farrell
Novel
AuIII(dien)(N-heterocycle) compounds, including the first
AuIIIN3(N-purine) examples,
are reported. The acidity of the dien ligand is affected by the nature
of the fourth ligand as a leaving group. The metal center of [Au(dien)(N-heterocycle)]3+ compounds was shown to be more stable to reduction than
when Cl– is present, with consequences for reactivity
with biomolecules: specifically, significant enhancement of π–π-stacking
interactions with tryptophan relative to isostructural and isoelectronic
platinum(II) and palladium(II) compounds.