American Chemical Society
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Synthesis and Properties of BF2‑3,3′-Dimethyldiarylazadipyrromethene Near-Infrared Fluorophores

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journal contribution
posted on 2013-07-05, 00:00 authored by Dan Wu, Donal F. O’Shea
The first synthesis of both organic and aqueous soluble BF2 chelated 3,3′-dimethyl-5,5′-diarylazadipyrromethenes has been achieved. The fluorophores are emissive in organic and aqueous solvents with high quantum yields in the key biological near-infrared (NIR) spectral region of 675–700 nm. Following efficient cellular uptake from aqueous media the fluorophore can be readily visualized with confocal microscopy.