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Synthesis, Photophysical Characterization, and Enzymatic Incorporation of a Microenvironment-Sensitive Fluorescent Uridine Analog

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journal contribution
posted on 04.03.2011, 00:00 by Maroti G. Pawar, Seergazhi G. Srivatsan
The synthesis of a microenvironment-sensitive base-modified fluorescent ribonucleoside analog based on a 5-(benzo[b]thiophen-2-yl)pyrimidine core, enzymatic incorporation of its corresponding triphosphate into RNA oligonucleotides, and photophysical characterization of fluorescently modified oligoribonucleotides are described.