jo701554h_si_001.pdf (2.46 MB)
Download file

Syntheses of (S,S)-Reboxetine via a Catalytic Stereospecific Rearrangement of β-Amino Alcohols

Download (2.46 MB)
journal contribution
posted on 18.01.2008, 00:00 authored by Thomas-Xavier Métro, Domingo Gomez Pardo, Janine Cossy
The formal total synthesis of (S,S)-reboxetine has been realized by two different approaches using a stereospecific rearrangement of β-amino alcohols catalyzed by (CF3CO)2O.