American Chemical Society
sc9b06321_si_001.pdf (7.23 MB)

Sustainable and Practical Access to Epoxides: Metal-Free Aerobic Epoxidation of Olefins Mediated by Peroxy Radical Generated In Situ

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journal contribution
posted on 2020-01-07, 16:34 authored by Yufeng Wu, Xiaofei Tang, Jingnan Zhao, Cunfei Ma, Lei Yun, Zongyi Yu, Bo Song, Qingwei Meng
A sustainable and practical protocol to prepare epoxides has been established by using air as the oxidant in the presence of K2CO3 in isopropylbenzene (CM) at 80–140 °C. The olefins are successfully converted into their corresponding epoxides in yields of up to 99%. CM and K2CO3 are reused in the scale-up recycling experiments. A reaction mechanism dominated by the radical pathway is proposed according to the control experiments and kinetic analysis.