posted on 2021-12-25, 16:13authored byShuo-Hsi Tang, Antoine Venault, Li-Hui Chou, Ding-Hung Lan, Gian Vincent Dizon, Chun Hsieh, Chih-Chen Yeh, Cheng-Liang Liu, Yung Chang
Air
plasma and spray technology are common methods for surface
modification. In this study, air plasma is used to generate hydroxyl
groups on various material surfaces. Then random copolymers of styrene
and ethylene glycol methacrylate (PS-r-PEGMA) are
spray-coated to achieve coating densities ranging between 0.1 and
0.6 mg/cm2. PS50-r-PEGMA50 led to the best overall antifouling properties, while a
coating density of 0.3 mg/cm2 was enough to significantly
reduce biofouling. This surface modification technique enabled efficient
modification of a wide range of materials and biofouling reduction
by at least 75% on polymeric surfaces (polystyrene, polyvinylidene
fluoride, poly(tetrafluoroethylene), polydimethylsiloxane),
metallic surfaces (steel, titanium alloy), or ceramic surface (glass).
Applied to the modification of well plate used for blood-typing, this
antifouling modification permitted to greatly increase the signal
sensitivity (×4).