American Chemical Society
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Sulfone Coupling and Double-Elimination Strategy for Carotenoid Synthesis

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journal contribution
posted on 2005-11-11, 00:00 authored by Samar Kumar Guha, Sangho Koo
A highly efficient synthetic method of carotenoid compounds has been developed on the basis of the sulfone coupling and double-elimination strategy. This method highlighted the sulfone-mediated coupling with the novel C10 dialdehyde, 2,7-dimethyl-4-octenedial, which was easily prepared and efficiently utilized in the synthesis of the conjugated polyene chains.