posted on 2001-12-13, 00:00authored byBishan Zhou, Jinsong Guo, Samuel J. Danishefsky
In model studies directed to the total synthesis of Et743, a strategic S−C bond formation in systems 26 and 27 was demonstrated. It was
further shown that Pictet−Spengler cyclization leading to spiro product 33 exhibits very high stereoselection.