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Strategy for Contiguous Tetramination of Cyclohexanones with o‑Phenylenediamines with Elemental Sulfur and DMSO

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journal contribution
posted on 2019-08-06, 16:09 authored by Thanh Binh Nguyen, Le Anh Nguyen, Pascal Retailleau
The S8/DMSO combination was found to be an excellent oxidizing agent for ipso,α,β,γ-tetramination of cyclohexanones with two molecules of o-phenylenediamines in the presence of TFA as a catalyst. The strategy could be applied to pyrido cyclohexanes as a direct method to extend the fused heteroaromatic system.

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