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Download fileStereoselective Synthesis of the Diazonamide A Macrocyclic Core
journal contribution
posted on 2015-03-20, 00:00 authored by Ilga Mutule, Beomjun Joo, Zane Medne, Toms Kalnins, Edwin Vedejs, Edgars SunaStereoselective
synthesis of the right-hand heteroaromatic macrocycle
of diazonamide A features C16–C18 bond formation in the Suzuki–Miyaura
cross-coupling and atropodiastereoselective Dieckmann-type macrocyclization
as key steps. The Suzuki–Miyaura cross-coupling gave the best
yields when it was catalyzed by a palladium–dioxygen complex.
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