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Stereoselective Synthesis of Fluorinated 1,3-cis-Diaminocyclopentanes

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journal contribution
posted on 17.06.2011, 00:00 by Morgane Pasco, Roba Moumné, Thomas Lecourt, Laurent Micouin
Several fluorinated 1,3-diaminocyclopentanes, previously reported to be useful RNA structural probes, can be prepared in a diastereoselective manner from a single bicyclic hydrazine precursor, in 3 to 9 steps.