ol901964z_si_001.pdf (4.33 MB)
Stereoselective Construction of Substituted Chromans by Palladium-Catalyzed Cyclization of Propargylic Carbonates with 2-(2-Hydroxyphenyl)acetates
journal contribution
posted on 2009-10-15, 00:00 authored by Masahiro Yoshida, Mariko Higuchi, Kozo ShishidoHighly substituted chromans have been constructed in a highly stereoselective manner by a palladium-catalyzed reaction of propargylic carbonates with 2-(2-hydroxyphenyl)acetates. Enantioselective reactions also successfully proceeded to give the optically active chromans with high enantioselectivity.