jo050450f_si_001.pdf (1.21 MB)
Download file

Stannous Chloride in Alcohol:  A One-Pot Conversion of 2-Nitro-N-arylbenzamides to 2,3-Dihydro-1H-quinazoline-4-ones

Download (1.21 MB)
journal contribution
posted on 2005-08-19, 00:00 authored by Choong Leol Yoo, James C. Fettinger, Mark J. Kurth
A novel one-step synthesis of 2,3-dihydro-1H-quinazolin-4-ones from 2-nitrobenzamides is reported. These reactions are mediated by stannous chloride in 0.02 M methanolic or ethanolic HCl solution and proceed in good yields.