American Chemical SocietyBrowse
jo050450f_si_001.pdf (1.21 MB)
Download file

Stannous Chloride in Alcohol:  A One-Pot Conversion of 2-Nitro-N-arylbenzamides to 2,3-Dihydro-1H-quinazoline-4-ones

Download (1.21 MB)
journal contribution
posted on 2005-08-19, 00:00 authored by Choong Leol Yoo, James C. Fettinger, Mark J. Kurth
A novel one-step synthesis of 2,3-dihydro-1H-quinazolin-4-ones from 2-nitrobenzamides is reported. These reactions are mediated by stannous chloride in 0.02 M methanolic or ethanolic HCl solution and proceed in good yields.

History

Usage metrics

Read the peer-reviewed publication

Stannous Chloride in Alcohol:  A One-Pot Conversion of 2-Nitro-N-arylbenzamides to 2,3-Dihydro-1H-quinazoline-4-ones
The Journal of Organic ChemistryThe Journal of Organic Chemistry

Categories

Keywords

0.02 M methanolicConversionquinazolinarylbenzamideNitronitrobenzamidesynthesisquinazolineethanolic HCl solutionDihydroyielddihydroStannous Chloridestannous chloride

Licence

CC BY-NC 4.0

Exports