American Chemical Society
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Stabilizing Guanosine-Sterol Ion Channels with a Carbamate to Urea Modification in the Linker

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journal contribution
posted on 2009-04-02, 00:00 authored by Ling Ma, William A. Harrell, Jeffery T. Davis
The use of a bis-urea lithocholamide linker within a guanosine-sterol dimer resulted in formation of large and stable ion channels. The channels were longer-lived than those formed by the corresponding bis-carbamate.