American Chemical Society
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Solid-Phase Synthesis of 5-Biphenyl-2-yl-1H-tetrazoles

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journal contribution
posted on 2004-04-01, 00:00 authored by Olga Kivrakidou, Stefan Bräse, Frank Hülshorst, Nils Griebenow
The combinatorial synthesis of novel biphenyl tetrazoles is described. Key steps include the simultaneous biphenyl formation and phenol deallylation under Suzuki cross-coupling conditions as well as the tetrazole ring formation on solid support. A representative library of 20 biphenyl tetrazoles was synthesized.