American Chemical Society
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Skeletal Transformations of Terpenoid Forskolin Employing an Oxidative Rearrangement Strategy

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journal contribution
posted on 2024-04-03, 13:37 authored by Shihao Cheng, Chenhu Dong, Yujie Ma, Xiaoyu Xu, Yu Zhao
The skeletal transformations of diterpenoid forskolin were achieved by employing an oxidative rearrangement strategy. A library of 36 forskolin analogues with structural diversity was effectively generated. Computational analysis shows that 12 CTD compounds with unique scaffolds and ring systems were produced during the course of this work.