American Chemical Society
jo048411b_si_002.pdf (1.92 MB)

Simple and Efficient Synthesis of Substituted 2-Pyrrolidinones, 2-Pyrrolones, and Pyrrolidines from Enaminones of Baylis−Hillman Derivatives of 3-Isoxazolecarbaldehydes§,

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journal contribution
posted on 2005-01-07, 00:00 authored by Vijay Singh, Rashmi Saxena, Sanjay Batra
The enaminones, generated from derivatives of appropriately substituted Baylis−Hillman adducts of 3-isoxazolecarbaldehydes, undergo intramolecular ring-closure reactions to afford substituted 2-pyrrolidinones, 1,5-dihydro-2-pyrrolones, and N-substituted pyrrolidines in good yields.