American Chemical Society
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Silver Salt-Mediated Allylation Reactions Using Allyl Bromides

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journal contribution
posted on 2021-04-16, 20:31 authored by Xiaodong Xiong, Jonathan Wong, Ying-Yeung Yeung
A facile, efficient, and chemoselective synthesis of allylic amides has been developed. Allyl bromides were used as the precursors activated by silver triflate. A Ritter-type reaction readily proceeded to give various allyl amides under mild conditions. The reaction protocol was also applicable to different nucleophilic partners to give a wide range of allyl-substituted products in the absence of a base.