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Download fileSelective Actinide-Catalyzed Tandem Proton-Transfer Esterification of Aldehydes with Alcohols for the Production of Asymmetric Esters
journal contribution
posted on 2017-04-04, 12:19 authored by Heng Liu, Moris S. EisenActinide-catalyzed
tandem proton-transfer esterification between
aldehydes and alcohols is presented herein for the first time. It
represents a novel convenient and external-oxidant-free methodology
in the preparation of asymmetric ester compounds. Various kinds of
aldehydes and alcohols can be applied to this reaction, affording
the corresponding ester product in moderate to high yields. A plausible
mechanism was proposed on the basis of the kinetic, stoichiometric,
and deuterium-labeling studies.
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ester compoundsexternal-oxidant-free methodologyVarious kindsAldehydebasismechanismaldehydeester productAsymmetric Esters Actinide-catalyzed tandem proton-transfer esterificationstoichiometricSelective Actinide-Catalyzed Tandem Proton-Transfer Esterificationdeuterium-labeling studiesyieldpreparation