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Download fileSc(OTf)3‑Catalyzed Transfer Diazenylation of 1,3-Dicarbonyls with Triazenes via N–N Bond Cleavage
journal contribution
posted on 2014-10-17, 00:00 authored by Cong Liu, Jian Lv, Sanzhong Luo, Jin-Pei ChengA new
and efficient method for diazenylation reactions was developed
with a Sc(OTf)3-catalyzed nitrogen–nitrogen bond
cleavage process with triazenes. The transfer diazenylation reactions
accommodate a diverse range of active methylene substrates including
simple ketones to give aliphatic azo compounds that are of significant
potential as azo prodrugs in high yields under mild conditions.