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Download fileRuthenium-Catalyzed Cyclization of Anilides with Substituted Propiolates or Acrylates: An Efficient Route to 2‑Quinolinones
journal contribution
posted on 2014-07-03, 00:00 authored by Rajendran Manikandan, Masilamani JeganmohanA Ru-catalyzed cyclization of anilides
with propiolates or acrylates
affording 2-quinolinones having diverse functional groups in good
to excellent yields is described. Later, 2-quinolinones were converted
into 3-halo-2-quinolinones and 2-chloroquinolines. The proposed mechanism
was strongly supported by experimental evidence and deuterium labeling
studies.