Ruthenium-Catalyzed meta-Carboxylation
journal contribution
posted on 2017-11-28, 17:47 authored by Helen
L. Barlow, Christopher J. Teskey, Michael F. GreaneyThe meta-carboxylation of arenes containing pyridine
and other azine-directing groups is reported. Using carbon tetrabromide
as the C1 source, ruthenium(III) trichloride catalysis enables functionalization
of the arene meta-C–H position, affording
carboxy methyl ester products after in situ reaction
with methanol.
